CLINICAL TRIALS AND OBSERVATIONS Mortality rates, life expectancy, and causes of death in people with hemophilia A or B in the United Kingdom who were not infected with HIV
نویسندگان
چکیده
1Clinical Trial Service Unit and 2Cancer Epidemiology Unit, University of Oxford, Oxford; 3Haemophilia Centre, Churchill Hospital, Oxford; 4Department of Haematology, Birmingham Children’s Hospital National Health Service Trust, Birmingham; 5Department of Haematology, Manchester Royal Infirmary, Manchester; 6Haemophilia Centre, Royal Free Hospital, London; 7Haemophilia Centre, Edinburgh Royal Infirmary, Edinburgh, United Kingdom
منابع مشابه
CLINICAL TRIALS AND OBSERVATIONS Mortality rates and causes of death among all HIV-positive individuals with hemophilia in Canada over 21 years of follow-up
Many individuals with hemophilia were infected with human immunodeficiency virus (HIV) in the early 1980s through contaminated blood products. Most also were co-infected with hepatitis C virus (HCV). Deaths among the entire cohort of HIV-positive hemophiliacs in Canada up to 2003 are described. Using registry data, we analyzed Kaplan-Meier survival curves, determined the effect of age at HIV se...
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1University Hospital of Wales and School of Medicine, Cardiff University, United Kingdom; 2Manchester Royal Infirmary, Manchester, United Kingdom; 3Addenbrookes Hospital, Cambridge, United Kingdom; 4Queen’s Medical Centre, Nottingham, United Kingdom; 5Royal Victoria Infirmary, Newcastle, United Kingdom; 6Hallamshire Hospital, Sheffield, United Kingdom; 7Oxford Haemophilia Centre, United Kingdom...
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The development of inhibitory antibodies to factor VIII (FVIII) occurs in approximately 30% to 40% of patients with severe hemophilia A. Management options for patients with inhibitor include eradicating it via immune tolerance induction (ITI) or treating bleeding episodes with large quantities of hemostatic agents. ITI is costly, approaching $1 million for the average 5-year-old, but if succes...
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Department of Haematology, University Hospital of Wales, School of Medicine, Cardiff, United Kingdom; The UK National Haemophilia Database, Manchester, United Kingdom; Department of Haematology, Royal Hospital for Sick Children, Glasgow, United Kingdom; The Haemophilia Centre, The Royal London Hospital, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Unit...
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